In tpt,or the whole os?

Lua is often used as a compiler. There are also scripts that automatically build simple parts, usually used by the subframe community.

I am not sure what you mean by building a computer using lua.

What I thought of once is building simple logic, something like an interpreter, in lua, which lua itself then executes. TPT is only used as a display in this case.

Also, what do you mean about Synergy? It's a normal computer probably built by hand.